The No. 12 Clemson Tigers and No. 15 South Carolina Gamecocks are set to play a crucial rivalry game this Saturday afternoon during the Week 14 college football schedule. Both teams have re-entered the College Football Playoff conversation after several upsets last week, with Clemson favored by 2. 5 points in the Week 14 odds. This weekend also features two other ranked matchups: No. 18 Iowa State (-2. 5) hosts No. 24 Kansas State, and No. 20 Texas A&M (+5. 5) takes on No. 3 Texas. Which games should you consider for your Week 14 college football bets? Additional important Week 14 spreads include No. 5 Notre Dame (-7. 5) at USC, No. 2 Ohio State (-19. 5) vs. Michigan, and No. 6 Miami (-10. 5) at Syracuse. Notre Dame is coming off a decisive win over Army and can secure its place in the College Football Playoff with a victory on Saturday.
Before finalizing your Week 14 college football picks and predictions, check out the college football against the spread, over/under, and money-line predictions powered by the self-learning SportsLine AI. Developed using advanced artificial intelligence and machine learning by SportsLine's Data Science team, AI Predictions and Ratings are crafted for each game. These predictions are based on statistical learning from historical data and assessing the opponents' defense via a numeric matchup score out of 100. Once a prediction is complete, the AI rating is created using the prediction, matchup score, and market odds. For instance, you might see an A-rating on an over bet if a team faces weak defense, the prediction differs from the line, and odds are favorable. Moreover, SportsLine AI is the first fully automated model on SportsLine, constantly updating with the latest data and helping identify line discrepancies. Since last season's start, SportsLine's AI PickBot has achieved 2, 073 4. 5- and 5-star NFL picks. Anyone following it has seen significant gains at their preferred sports betting platforms. For Week 14 betting, the AI PickBot has evaluated the odds and provided picks for every game. Access the AI's predictions for the Week 14 schedule exclusively here. Top Week 14 AI picks include SMU, ranked No. 9, comfortably covering at home against California Golden Bears (-13. 5, 55. 5) in their 3:30 p. m. ET game Saturday. After losing to BYU in early September, SMU has won eight straight to secure its ACC title game spot. Despite potentially high stakes, they aren't expected to falter, as a loss could end their Playoff chances. Quarterback Kevin Jennings led with a career-high 323 yards and two touchdowns, plus one rushing touchdown, in a 33-7 victory over Virginia last week. Jennings heads an offense that exceeded 30 points in seven of its last eight games. The AI PickBot found value in SMU and projects a 38-22 victory, meriting an A-rating. Discover more Week 14 predictions and picks at SportsLine. Make your Week 14 college football picks using AI insights, which include 18 additional A-rated spread picks. Check out the AI PickBot's selections before placing your bets. Access them exclusively at SportsLine.
Week 14 College Football: Clemson vs South Carolina & AI Predictions
                  
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