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Feb. 25, 2025, 11:29 p.m.
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China's Akeso Launches Groundbreaking Lung Cancer Drug Outperforming Keytruda

China's DeepSeek recently made headlines with groundbreaking innovation at an incredible price, a trend that has also emerged within the pharmaceutical sector, notably through a little-known Chinese biotech firm called Akeso. In September, Akeso launched Ivonescimab, a new lung cancer drug that outperformed Keytruda, Merck's blockbuster drug, in clinical trials, reportedly allowing patients to go 11. 1 months before their tumors resumed growth, compared to 5. 8 months for Keytruda. This success led to a dramatic rise in shares for Summit Therapeutics, Akeso’s U. S. partner, which has licensed the drug for North America and Europe. Despite its significance, Akeso's achievement initially went unnoticed by the broader public until DeepSeek's innovations highlighted China’s growing influence in global biotechnology. Akeso’s CEO, Michelle Xia, expressed confidence that the Chinese biotech sector will increasingly impact the global market. Akeso attributes its success to a profound understanding of disease biology and protein engineering, combined with rapid development capabilities bolstered by China’s talent pool. Historically, Chinese pharmaceutical firms primarily produced generic medications until recent years when they began developing competitive, innovative drugs and securing significant international partnerships.

For instance, AstraZeneca and Merck have made multi-billion dollar agreements with Chinese companies for drug development. Research indicates that China's biotech landscape is rapidly evolving, with licensing deals skyrocketing from 46 in 2017 to over 200 last year, reflecting the nation's status as an emerging innovation hub. Despite these advancements, skepticism regarding the quality of domestically produced drugs persists in China, leading to concerns about generic medicines, which sparked investigations due to quality claims. Many Chinese patients remain unaware of Akeso or prefer imported medications, associating higher price with better quality. While Akeso's drug is presently approved in China for certain lung cancer cases, it is still years away from U. S. availability. A global trial is set to commence, potentially reinforcing the progress made by Chinese biotech in developing top-tier pharmaceutical products.



Brief news summary

Akeso, a fast-growing Chinese biotech firm, is attracting significant attention with its novel lung cancer treatment, Ivonescimab. Recent clinical trial outcomes demonstrate that the drug offers a median progression-free survival of 11.1 months, notably surpassing Merck's Keytruda, which provides 5.8 months. This positive development has positively impacted the stock of Summit Therapeutics, Akeso's U.S. partner, which has licensing rights for North America and Europe. Analysts view this period as a transformative moment for China's pharmaceutical sector, drawing parallels with rapid advancements in technology. Traditionally, China's biotech industry was primarily focused on "me-too" drugs; however, emerging collaborations with Western companies are paving the way for more original treatments. This transition highlights China's increasing global influence, even as skepticism regarding the quality of its pharmaceuticals persists, with many consumers opting for pricier foreign alternatives. As Ivonescimab approaches regulatory approval and global clinical trials are planned, Akeso's advancements could solidify China's position as a significant player in international drug development.
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