With three weeks left in the 2024 NFL season, three of the four AFC divisions are already clinched, while all NFC divisions remain contested. The Eagles (12-2) aim to be the first to secure a home playoff game on Sunday with a 1 p. m. ET kickoff at the Commanders (9-5). Philadelphia is a 4. 5-point favorite, up from the initial line, with an over-under of 46. 5. The Eagles boast a 7-1 record against the spread on the road, while Washington is 5-2 at home. The forecast for Eagles vs. Commanders predicts sunny skies, temperatures in the 30s, and light northwest winds. Before making any NFL picks for Week 16, consult the NFL predictions powered by SportsLine's AI, which includes money line, over-under, and against the spread insights. Developed by SportsLine's Data Science team, the AI utilizes advanced machine learning and artificial intelligence to generate predictions by analyzing each team's historical data and evaluating the opponent's defense with a matchup score out of 100. The AI rating combines the prediction, matchup score, and market odds. For instance, an A-rating may be seen on an over bet if a team faces a weak defense, their prediction deviates from the line, and the odds are favorable. SportsLine AI is a cutting-edge predictive model that continuously updates with new data to identify line discrepancies.

The AI PickBot has delivered 2, 131 successful 4. 5- and 5-star prop picks since last season's start, significantly benefiting those who follow it on top betting platforms. For Week 16, the AI PickBot evaluated NFL odds and provided picks for all 16 games. The AI's Week 16 NFL schedule predictions are exclusively available here. Top Week 16 NFL AI picks Analyzing every Week 16 game, the AI PickBot favors the Cowboys to cover comfortably as 4-point home underdogs against the Buccaneers on Sunday Night Football, with an over-under set at 48. Despite a mid-season five-game skid, Dallas has shown resilience, covering the spread in three of their last four games and hitting the over in five of seven home games. Led by Cooper Rush, Dallas has secured victories in three of four recent games, including as underdogs against the Commanders and Panthers. Rico Dowdle has revitalized the running game, rushing for over 100 yards in three consecutive games—the first undrafted running back to achieve this since Arian Foster in 2014. With the Buccaneers ranking 22nd in the NFL in yards allowed per carry (4. 5), another heavy dose of Dowdle is likely on Sunday. This is why AI PickBot gives a Cowboys cover an A+ rating and predicts a 35-29 Dallas win on average. Check SportsLine for more Week 16 football predictions and picks. How to make Week 16 NFL picks The AI PickBot has also generated 16 coveted A+ picks for Week 16. Review the AI PickBot's NFL predictions before placing your bets for Week 16. Access them exclusively at SportsLine.